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International Journal of Pediatrics and Neonatology

Vol. 5, Issue 1, Part A (2023)

Prevalence of congenital heart defects in infants of diabetic mothers in Aseer region, Southwestern, Saudi Arabia

Author(s):

Mohammed Abdullah Algossadi, Walid Abdel Wahab Eid, Renad Mohammed Alshehri, Reema Mohammed Alshehri and Abdulaziz Mohammed Alshehri

Abstract:

Background: Maternal diabetes mellitus is a risk factor for adverse maternal and fetal outcomes, including anatomical malformations such as congenital heart defects (CHD). 
Objectives: To determine the prevalence of CHD in babies born to mothers with pre-existing or gestational diabetes. 
Patients and Methods: A retrospective study of all births of type 1, type 2 diabetic mothers, gestational diabetic mothers, and non-diabetic mothers admitted to the newborn nursery and the neonatal intensive care unit between July 2011 and June 2022 was performed. 
Results: A total of 2079 mothers and their offspring were enrolled in the study. Of 2079 mothers 1397 (67.2%) were non-diabetic and 682 (32.8%) were diabetic. In terms of diabetic status, the incidence of cardiovascular anomalies in infants of diabetic mothers is significantly higher than the infants of non-diabetic mothers (p<0.0001). The most frequent echocardiographic findings were patent ductus arteriosus (38.3%), hypertrophic cardiomyopathy (37.1%), and ventricular septal defect (32.7%). 
Conclusions: The incidence of CHD in infants of diabetic mothers is significantly higher than in infants of non-diabetic mothers. Screening diabetic mothers for fetal cardiac malformations seems highly advisable in such cases.
 

Pages: 10-14  |  281 Views  65 Downloads

How to cite this article:
Mohammed Abdullah Algossadi, Walid Abdel Wahab Eid, Renad Mohammed Alshehri, Reema Mohammed Alshehri and Abdulaziz Mohammed Alshehri. Prevalence of congenital heart defects in infants of diabetic mothers in Aseer region, Southwestern, Saudi Arabia. Int. J. Pediatr. Neonatology 2023;5(1):10-14. DOI: 10.33545/26648350.2023.v5.i1a.30
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