Belkasem A, Abdurahman, Hadid Ibtisam
Obesity is one of the global epidemics in children and adult. Children with Congenital Adrenal Hyperplasia (CAH) have a higher risk of obesity. CAH is a group of genetic condition that affects adrenal gland steroidogenesis. Classic congenital adrenal hyperplasia (CAH) is a rare, life threatening, endocrine disorder that affects boys and girls equally. There are few studies reporting on higher rates of overweight and obesity among children with CAH. Lack of such study in Libya warrants the researcher to undergo this study. Data were collected from the total 56 patients (36 with CAH include Classic salt wasting and Simple Virilizing types and 20 normal/control group) with 6-15 years young children who attended at Tripoli University Hospital, Tripoli, Libya for one year from September 2018 to August 2019. The effect of CAH is severe in young age, more prevalence in girls than boys and more cases diagnosed at the 0-1 year young with simple virilizing type. BMI and Lipid profile have no much role in the increase of severity in number of cases. Family history like Obesity and CAH play a major role among the children. CAH affected children have high BP. Ideal dose of Hydrocortisone (HC) for the early treatment of CAH is about 10-15mg/m2/day. Careful dosing during early childhood is needed to prevent increased weight gain and an early adiposity rebound. Larger and longer-term studies are needed to confirm our results.
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